Protected: Literature for 12/18

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Lecture for November 20th, 2013: Which patients with pharyngitis should be treated with antibiotics?

This month, we will consider whether antibiotic use for pharyngitis is justified by reviewing a SMARTEM podcast, and reviewing the papers listed below.

Listen to the SMARTEM podcast here: Treatment of Acute Pharyngitis. Please listen to 12:30-46:28 for the most relevant parts.

Papers to be reviewed:

Del Mar CB.  Antibiotics for sore throat. Cochrane Database Syst Rev. 2011;(9). (This is a very long paper, we are only going to discuss through acknowledgements on the 13th page of the paper or the 16th page of the attached document)

Fine AM et al.  Large Scale Validation of the Centor and McIssac Scores to Predict Group A Streptococcal Pharyngitis.  Arch Int Med 2012;172(11):847-852.

Please enjoy!

Lecture for October 2nd, 2013: Does time equal brain in ischemic stroke?

This month, we will tackle the question of whether or not “time=brain” in acute ischemic stroke by reviewing a SMARTEM podcast, and the papers listed below.

Listen to the SMARTEM podcast here: SMART Thrombolytics for Stroke: Update

Papers to be reviewed:

Saver JL, Fonarow GC, Smith EE, et al. Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke. JAMA. 2013 Jun 19; 309(23): 2480-8.

Sandercock P, Wardlaw JM, Lindley RI, et al. The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial. Lancet. 2012 Jun 23; 379(9834): 2352-63.

We will also review the ACEP clinical policy for TPA use.


Lecture for September 4th, 2013: Should anyone use CVP anymore?

This month, given the amount of critical care time we face at NMH and the discussions on rounds, we will consider the utility of CVP as a guide to fluid resuscitation and as a clinical marker by reviewing the papers below, and an EMCRIT podcast.

Listen to the EMCRIT podcast here: Fluid Responsiveness with Dr. Paul Marik

Papers to be reviewed:

Marik PE and Cavallazzi R. Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Crit Care Med. 2013 Jul;41(7):1774-81.

Marik PE, Monnet X, Teboul JL. Hemodynamic parameters to guide fluid therapy. Ann Intensive Care. 2011 Mar 21;1(1):1.